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Brucella melitensis Gram-stain that causes zoonotic disease 
Brucella melitensis Gram-stain that causes zoonotic disease 
This section provides information on one of the nine zoonotic diseases which have been identified by a experts in a national consultation organised by RCZI in June, 2008  as focus or priority diseases for the next five years.

Brucellosis, a bacterial disease caused by members of the genus Brucella, is an important zoonosis and a significant cause of reproductive losses in animals.

Brucella speciesare associated with a high morbidity rate in naïve herds, and a much lower morbidity rate in chronically infected herds. In naive cattle, B. abortus spreads rapidly, and 30% to 80% of the herd may abort. In herds where this organism has become endemic, only sporadic symptoms occur and cows may abort their first pregnancies. A similar pattern is seen with B. melitensis-infected sheep and goats and B. suis infected pigs. Fertility can be permanently impaired after infection with some species of Brucella. The main impact is (thus) economic; deaths are rare except in the fetus and neonate.

Also called undulant fever, or Maltese fever, Brucellosis is a highly contagious zoonosis for humans caused by ingestion of unsterilised milk or meat from infected animals, or close contact with their secretions. Brucellosis is usually an occupational disease; most cases occur in abattoir workers, veterinarians, hunters, farmers, reindeer/caribou herders and livestock producers. Brucellosis is also one of the most easily acquired laboratory infections.
Researchers   Global Situation Researchers   Regional/ India Situation
World Health Organization

Pappas G, Papadimitriou P, Akritidis N, et al. The new global map of human brucellosis. Lancet Infect Dis. 2006;6(2):91–9

Mantur BG and Amarnath SK. Brucellosis in India – a review. J. Biosci 2008; 33(4): 539–547

Aulakh HK et al. A Study on the Epidemiology of Bovine Brucellosis in Punjab (India) Using Milk-ELISA. ACTA VET. BRNO 2008, 77: 393–399; doi:10.2754/avb200877030393.

Brucellosis in India: a deceptive infectious disease, Henk L. Smits & S. Manzoor Kadri, Indian J Med Res 122, November 2005, pp 375-384

Dhand NK et al. A study on the epidemiology of brucellosis in Punjab (India) using Survey Toolbox. Rev. sci. tech. Off. int. Epiz., 2005, 24 (3), 879-885

Renukaradhya GJ, Isloor S and Rajasekhar M. Epidemiology, zoonotic aspects, vaccination, control/eradication of brucellosis in India: Vet Microbiol. 2002;90(1-4):183-95

Researchers   Public Health Measures Researchers   Animal Health
Surveillance standards

Brucellosis in humans and animals. WHO

World Health Organization – vaccine safety and development information

Zoonotic diseases of public health importance. Zoonoses Division. National Institute of Communicable Diseases. New Delhi. 2006

Fast facts

Comprehensive information

Diagnostic manual

Control and trade recommendations

Godfroid J. Brucellosis in wildlife. Rev. sci. tech. Off. int. Epiz., 2002, 21 (2), 277-286
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